Niacin for Life
Address brain health, kidney dysfunction, improve lipid profile, reduce blood pressure, reduce liver fat, all without pharmaceuticals.
Our comprehensive consultation services has the potential to help you achieve optimal blood and kidney health in less than 3 months.
Schedule Consultation
Address Kidney Dysfunction

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Basic biochemical approaches directly address and correct pathogenic processes
We'll assess your current kidney function and provide guidance using non-pharmaceutical approaches.

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Personalized Action Plan
We will create a tailored plan to potentially improve your GFR and overall kidney health.

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Consistent Progress Tracking
Regular check-ins and lab tests to monitor your improvement and make adjustments as needed.
KIDNEY DEFENDER
Improve Lipid Profile with Niacin Therapy
Reduce Triglycerides
Our approach can lower triglycerides by up to 50% without the use of statins.
Lower LDL & Lp(a)
Optimize your LDL levels by 40% or more and lower one of the most important biomarkers, Lp(a).
Boost HDL Cholesterol
Increase your protective HDL cholesterol for improved cardiovascular health.
Reduce Blood Pressure

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Niacin & related
Niacin has demonstrably reduced blood pressure along with other basic non-pharmaceutical supplements.

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Dietary Changes
Optimize your intake of sodium, potassium, and other nutrients to lower BP.

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Physical Activity
Gentle exercise has the potential to improve circulation and blood pressure regulation.
Reduce Liver Fat
Guided niacin supplementation
Potentially reduce fatty liver by as much as 50% in some individuals.
Dietary Modifications
Adjust your diet to reduce intake of refined carbs and increase fiber, protein, and healthy fats.
Lifestyle Changes
Incorporate regular exercise, stress management, and adequate sleep to support liver function.
High dose niacin therapy guidance and education
Required for gene functions and life
Niacin is converted to NAD, the vitamin-defining molecule required for > 400 gene functions, which is far more than any other vitamin.
Empower the niacin-flush
Understand the clinically proven benefits of the flush response and how control the flush response so it is pleasant to you.
Niacin clinical trials
Niacin has been proven to cure mitochondrial myopathy and is required to address neurological dysfunctions.
Comprehensive Consultation Services
Our Personalized Approach
We take the time to thoroughly understand your unique health needs and goals, then create a customized plan to address them without the use of pharmaceuticals.
Ongoing Support and Guidance
  • Regular check-ins and progress monitoring
  • Tailored lifestyle and dietary recommendations
  • Access to integrative experts
  • Ph. D., Biochemistry
  • Over 10 years experience contributing to the orthomolecular medical community
  • Author:
  • Niacin, The Real Story (prefances)
  • The Vitamin Cure for Arthritis
  • University book chapters on niacin, riboflavin, thiamine, & biotin
  • Over 10 years of experience in continuing medical education for physicians, specialists, & healthcare practitioners
Get Started Today
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Schedule Consultation
Book your initial appointment to discuss your health concerns.
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Personalized Assessment
We'll conduct a comprehensive evaluation to understand your needs.
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Customized Action Plan
Our experts will develop a tailored plan to achieve your goals.
Qualifications for Integrative Health
  • W. Todd Penberthy, PhD​
  • WTPENBER@GMAIL.COM
  • 1(689) 247-0254
  • Extensive Education in Integrative Approaches: I have a doctorate in biochemistry and over 10 years of experience in the orthomolecular community, with a deep understanding of the biochemical processes that underlie health and disease.
  • Mentored by Abram Hoffer, MD, PhD
  • Author of university textbook chapters on niacin, riboflavin, and thiamin
  • Published research focused on niacin/NAD, autoimmune disease, and neurodegenerative diseases
  • Vitamin B1 (thiamine), B2 (riboflavin), and B3 (niacin) dependent gene functions database
  • Over 10 years in medical education: I am qualified to provide tailored guidance on nutrition, exercise, and other lifestyle factors that support optimal health.
William Todd Penberthy, Ph. D.
Winter Park, Florida, United States of America
Mobile: 1(689) 247-0254 • Email: WTPENBER@GMAIL.COM
EDUCATION
Ph.D., Biochemistry, University of Tennessee, Memphis, TN
B.S., Biology, University of Central Florida, Orlando, FL
PROFESSIONAL EXPERIENCE
Medical Writer, 2012 - current, Winter Park, FL
Professor, 2009-2012, University of Central Florida, Orlando, FL
Professor, 2004-2009, University of Cincinnati, Cincinnati, OH
Post-doctoral Fellow, 2000-2003, University of California, Los Angeles, CA
Post-doctoral Fellow, 1999-2000, Tufts University, Boston, MA
THERAPEUTIC AREAS
Orthomolecular medicine, oncology, neurodegenerative disease, cancer, cardiovascular disease, diabetes, arthritis
SUMMARY 16+ years writing/research in the biomedical scientific realm
  • NAD/Niacin/Vitamin B3 expertise
  • Textbook chapters:
  • Continuing medical education (CME) writer to educate physicians/maintain board certifications:
  • Integrative Psychiatry courses; anxiety, depression, and ADHD
  • CME credit grant applications
  • Medical Conference Coverage: ASH 2019; ASBMR 2019, AAP 2018; ADA 2018; WAC 2018 (AAAAI/WAO); ASM Microbe 2017; ENDO 2017; AAES 2017; HFS 2016; ITC 2015; World Congress on Breast Healthcare 2015; IBD 2020 (2014); ACP 2014; NAMCP 2014; SCAI 2013; CMSC/ACTRIMS 2013
  • Weekly top biomedical science newspiece from: Science Translational Medicine, other Science journals, Nature, PNAS, Neuron, other journals
  • Medical writer/researcher of physician clinical overviews for MDs: B-cell lymphoma, carcinoid, desmoid tumors, hyperleukocytosis in malignancy, Malignant brain tumors in children, aspiration pneumonia, Bartonella infections, salmonellosis, protein C deficiency, prostatitis, Raynaud’s phenomena, more
  • Needs Assessments: diabetes, systemic lupus erythematosus, pediatric multiple sclerosis, schizophrenia, insomnia disorders, generalized tonic-clonic seizures, cystic fibrosis
  • Medical technology directory reports: Comprehensive reviews focused on cutting edge medical technologies for practice/budgetary/policy decisions. Subscription only.
  • Guest executive editor: Current Pharmaceutical Design 2009; Invited reviewer for peer-reviewed journals
SELECTED PUBLICATIONS
McConnel, Stephen and W. Todd Penberthy (2021). Reversing Chronic Kidney Disease with Niacin and Sodium Bicarbonate. Orthomolecular Medical News Service.
Penberthy, W. Todd, and James B. Kirkland (2020 & 2012). Niacin. Present Knowledge in Human Nutrition. 10th edition, Diane Birt, J W Erdman, I MacDonald, S H Zeisel, eds. (Ames, Iowa, International Life Sciences).
Penberthy, W. Todd, Mahrou Sadri, and Janos Zempleni (2020 & 2012). Biotin. Present Knowledge in Human Nutrition. 10th edition, Diane Birt, J W Erdman, I MacDonald, S H Zeisel, eds. (Ames, Iowa, International Life Sciences).
Penberthy, W.Todd (2020 & 2013). Niacin, Riboflavin, and Thiamine, ed. Stipanuk, M.H., Caudill, M.A., eds., Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 3rd ed. Elsevier/Saunders, St. Louis, Mo., pp. p.540-564.
Penberthy, W. Todd, and Robert Smith (2018). Nutritional Approaches Treatments for Multiple Sclerosis. Orthomolecular Medical News Service. 
Hu, L, K. Ibrahim, M. Stucki, M. Frapolli, N. Shahbeck, F. A. Chaudhry, B. Gorg, D. Haussinger, W. Todd Penberthy, T. Ben-Omran, and J. Haberle (2015). Secondary NAD+ Deficiency in the Inherited Defect of Glutamine Synthase. Journal of Inherited Metabolic Disease. 38(6):1075-83.
Penberthy, W. Todd & Robert Smith (2015). The Vitamin Cure for Arthritis. A book for laypersons about nutritional approaches to treating arthritis. p1-237.
W. Todd Penberthy (2013). Ask This Question Before Taking Statins. Orthomolecular Medical News Service.
Babak Baban, W. Todd Penberthy & Mahmood S. Mozaffari (2010). The Potential Role of Indoleamine 2,3 Dioxygenase (IDO) as a Predictive and Therapeutic Target for Diabetes Treatment: a Mythical Truth; EPMA Journal 1:46–55.
Penberthy, W. Todd (2009). Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors Towards Therapeutic Glucocorticoid Mimetics for Potential Treatment of Multiple Sclerosis; PPAR Research 853707-.
Penberthy, W. Todd (guest executive editor) Current Pharmaceutical Design, published 2009. Developed theme, coordinated authors/reviewers, and provided oversight to completion. Theme: NAD Biology in Disease.
Penberthy, W. Todd & Tsunoda, I. (2009). The Importance of NAD in Multiple Sclerosis. Current Pharmaceutical Design. 2009; 15(1): 64-99.
Penberthy, W. Todd (2009). Nicotinamide Biology and Disease. Current Pharmaceutical Design; 15 (1) 1-2.
Kevin S Jones, Alexander P Alimov, Horacio L Rilo, Ronald P Jandacek, Laura A Woollett, and W. Todd Penberthy (2008). A High Throughput Live Transparent Animal Bioassay to Identify Non-toxic Small Molecules or Genes that Regulate Vertebrate Fat Metabolism for Obesity Drug Development. Nutrition and Metabolism. 5:23.
Penberthy, W. Todd. (2007). Pharmacologic Targeting of IDO-mediated Tolerance for Treating Autoimmune Disease. Current Drug Metabolism. 8: 245-266. REQUEST PDF AND I WILL SEND.
Traver, David, Barry H. Paw, Kenneth D. Poss, W. Todd Penberthy, Shuo Lin, and Leonard I. Zon (2003). Transplantation and in vivo Imaging of Multi-lineage Engraftment in Zebrafish Bloodless Mutants. Nature Immunology. 4:1238-1246.
Penberthy, W. Todd, Ebrahim Shafizadeh, and Shuo Lin (2002). The Zebrafish as a Model for Human Disease. Frontiers in Biosciences 7, D1439-53.
PROFESSIONAL ORGANIZATIONS
Orthomolecular Medical News Service (OMNS)
American Medical Writers Association (AMWA)
American Association for the Advancement of Science (AAAS)
Global Alliance of Publication Professionals (GAPP)
Presentations & Meetings
  • Invited presentation to the Mayo Clinic, May 2009, “NAD-Centric Pharmacologic Approaches & Obesity/COPD Animal Modeling Using Zebrafish.”
  • Invited presentation and Travel Award to The 4th Annual Metabolic Diseases World Summit, Boston, MA 2008: “A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development”
  • Invited speaker at Case Western TREC Retreat 2008, “NAD Pharmacotherapeutics: Zebrafish-based Small Molecule Studies of Lipid Metabolism with Implications for Cancer and Multiple Sclerosis.”
  • Invited presentation and Travel Award to PARP 2008, Tucson, Arizona
  • Invited speaker at the Department of Human Nutrition at Ohio State University: “The Zebrafish Genetic Model Organism for Studying Nutrient Function,” Oct. 2007, Columbus, Ohio
INVITED JOURNAL REVIEWER
Diabetes, PPAR Research, Mutation Research, Developmental Dynamics, Immunology Letters, Journal of Nutrition, Antiviral Research, Brain Research Bulletin, Schizophrenia Research, Molecular Biology Reports, Development, Nucleic Acid Research
Testimonial
Testimonial 6/15/21
Providing Scientific Information that Changed My Life
As a caring colleague, Dr. Penberthy reached out to me following my leukemia treatment to make sure I was aware of the benefits of the nutraceutical inositol hexaphosphate (IP6) for ensuring remission in cancer survivors. Though successfully in remission just a year out from intensive chemotherapy, I was already beginning to exhibit some of the worrisome signs that presaged the initial onset of the disease. My oncologist had warned me that should I relapse, the most likely 2nd round of treatment would be extensive radiation treatment to destroy my bone marrow followed by a bone marrow transplant, a truly grueling procedure with a less than desirable survival rate. After reading the strong literature on IP6 that Dr. Penberthy recommended, I began a daily regimen and not only did my leukemia symptoms (first cutaneous "purpura", then later a positive "molecular PCR" test) disappear, my energy level improved markedly.
That was 10 years ago, and I credit Todd with saving my life. My oncologist at that time knew nothing of IP6 because it is too cheap a product to justify pharmaceutical company sponsorship and marketing to medical professionals. Having conducted scientific research in academia, Dr. Penberthy is well positioned to facilitate the connection between the science that has been published on nutraceuticals, and the physicians who are treating patients but who have little time to read the literature in depth.
Christine L. Miller, Ph.D.
Baltimore, Maryland
Vitamin B3 (niacin/NAD)-dependent gene functions database

PDF file

Supplementary Table 1-B3:NAD-utilizingGenes.xls - Compatibility Mode.pdf

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